• Tags: retina
AOA report analyzes ocular risks of GLP-1RAs
Research

AOA report analyzes ocular risks of GLP-1RAs

Released during the 2025 Optometry’s Meeting, this comprehensive rundown dives into potential rare ophthalmic side effects associated with use—and offers clinical care recommendations.
Earlier diabetes diagnosis may lead to worsening DR progression
Research

Earlier diabetes diagnosis may lead to worsening DR progression

Study identifies mechanisms for the potential protective effect of later diabetes diagnosis on DR severity.
Study identifies risk factors for myopic macular degeneration progression
Research

Study identifies risk factors for myopic macular degeneration progression

Axial elongation was shown to be a key risk factor for progression, among others.
Amaros secures Series A financing for AI ophthalmic evidence platform
Business

Amaros secures Series A financing for AI ophthalmic evidence platform

Financing will support adoption and commercialization of the EvidenceEngine to accelerate clinical trial enrollment and generate real-world evidence on retinal disease.
GLP-1 drug users twice as likely to develop nAMD
Research

GLP-1 drug users twice as likely to develop nAMD

New research findings also report risk was 3 times as high among diabetic patients with the longest exposure to GLP-1 RAs.
FDA clears Ocugen for phase 2/3 trial on Stargardt gene therapy
Pipeline

FDA clears Ocugen for phase 2/3 trial on Stargardt gene therapy

IND approval enables continued clinical evaluation of OCU410ST, a modifier gene therapy with a favorable safety and tolerability profile; plans include a 2027 BLA submission.
Study ties magnesium to reduced RVO risk
Research

Study ties magnesium to reduced RVO risk

Sufficient magnesium intake significantly reduced risk of RVO, particularly in three key subgroups.
Does silicone oil cause macular edema post-RRD surgery?
Research

Does silicone oil cause macular edema post-RRD surgery?

Study identifies two key factors that may significantly increase the risk for macular edema development.
ViGeneron rebrands as VeonGen Therapeutics with new FDA designation
Pipeline

ViGeneron rebrands as VeonGen Therapeutics with new FDA designation

German-based genetic medicine company also receives a Rare Pediatric Disease Designation for its Sargardt disease gene therapy candidate.
Opus Genetics reports positive phase 3 data for phentolamine 0.75%
Pipeline

Opus Genetics reports positive phase 3 data for phentolamine 0.75%

Topline findings indicate the gene therapy achieved a ≥15-letter (≥3-line) gain in mesopic low contrast distance visual acuity versus placebo.
FDA grants Rare Pediatric Disease designation to Stargardt gene therapy
Pipeline

FDA grants Rare Pediatric Disease designation to Stargardt gene therapy

OCU410ST could receive a priority review voucher if approved; company plans to initiate a phase 2/3 trial in coming weeks—along with a BLA filing in 2027.
Therini Bio raises nearly $40M to study DME and Alzheimer's immunotherapeutics
Business

Therini Bio raises nearly $40M to study DME and Alzheimer's immunotherapeutics

Funding to support two trials on fibrin-targeting immunotherapies targeting vascular dysfunction-induced neuroinflammation in severe retinal and neurological diseases.
FDA approves Genentech's Susvimo for DR
Products

FDA approves Genentech's Susvimo for DR

First sustained-release delivery system of ranibizumab earns third indication, with injections needed just once every 9 months.
Atsena releases favorable LIGHTHOUSE trial data on XLRS gene therapy
Pipeline

Atsena releases favorable LIGHTHOUSE trial data on XLRS gene therapy

Positive findings from 1-year post-treatment show meaningful improvements on visual function measurements, with foveal schisis closure observed in 67% of patients.
New alliance seeks a shift in healthcare via AI-based oculomics
Research

New alliance seeks a shift in healthcare via AI-based oculomics

Healthcare leader-led consortium Alliance for Healthcare from the Eye calls for a proactive healthcare approach, with a focus on prescreenings for ocular and systemic health.
How safe are iPSC-based RPE strip transplants for patients with RPE degeneration?
Research

How safe are iPSC-based RPE strip transplants for patients with RPE degeneration?

First clinical report of allogeneic iPSC-derived RPE strip transplantation demonstrated success in all three patients.
Zeiss debuts new research data platform for integrated workflows
Products

Zeiss debuts new research data platform for integrated workflows

Company’s cloud-based solution uses AI technology to integrate accessible clinical and research data into clinicians’ daily routines.
LumiThera Valeda system extension trial data expands dry AMD vision improvements
Research

LumiThera Valeda system extension trial data expands dry AMD vision improvements

Presented at ARVO, new findings support earlier initiation and extended vision benefits of Valeda Light Delivery System out to 4.5 years.
Favorable safety data supports Alkeus' oral gildeuretinol for dry AMD
Pipeline

Favorable safety data supports Alkeus' oral gildeuretinol for dry AMD

Presented during ARVO 2025, the modified form of Vitamin A demonstrated a slower decline in vision-related quality of life among patients diagnosed with GA secondary to AMD.
Potential connection ties AMD to higher CVD risk
Research

Potential connection ties AMD to higher CVD risk

Any stage of AMD linked with a 2.37-fold increased risk of cardiovascular disease.