AEYE Health announced a nationwide expansion of the digital health company’s portable artificial intelligence (AI)-based eye screening technology integration with a major U.S. electronic medical record (EHR) platform: Epic.
First, a look at AEYE Health.
The New York-based, venture-backed company is best known for its development of fully autonomous, AI-based retinal imaging and diagnostics technology for retinal imaging.
Its portfolio extends to two key products:
- AEYE Diagnostic Screening (AEYE-DS)
- Includes the Aurora AEYE portable camera, launched in partnership with Optomed
- AEYE Comprehensive Screening (AEYE-CS)
Take note, however: Only the AEYE-DS has received FDA 501(k) clearance.
Talk about this screening technology.
Granted FDA clearance in both 2022 and 2024, AEYE-DS is designed as a point-of-care screening solution to detect more-than-mild diabetic retinopathy (DR) in diabetes patients ages 22+ with no prior DR diagnosis.
How it works: The system captures images from both eyes of a patient (using just one image per eye) via either a portable or desktop camera and uses AI to analyze the retinal data.
- The timing: Diagnostic results are available in just 1 minute (vs standard screenings, which can take 15 to 20 minutes).
And just how accurate are these results?
Pretty darn accurate: Over 90% for sensitivity and specificity, using either desktop and portable cameras
The evidence: First-of-its-kind phase 3 clinical research
- See here for those details—and click here for peer-reviewed research.
Now to Epic.
Epic System’s Epic EMR has a reputation as one of the largest—and most widely used—EMR / electronic health record (EHR) programs in the U.S. healthcare system.
- Case in point: As of June 2025, a reported +3.6K hospitals were utilizing Epic’s EHR, accounting for just under 38% of the U.S. inpatient EHR market share.
The comprehensive healthcare software suite manages and unifies patient data, engagement, clinical workflows, billing, and other clinical information to increase accessibility across healthcare organiations—all via a single, central digital hub.
And the integration?
According to AEYE Health, its “improved integration” with Epic kicked off prior to the newly-announced expansion (though the exact timeframe is unclear).
And now with this expanded deployment of the company’s portable AI screening:
- Healthcare providers (HCPs) utilizing Epic will be able to order exams and results in real time—enabling “DR screenings in under 1 minute directly within the Epic EMR and without disrupting clinical workflows,” according to AEYE.
Which HCPs would this include?
Any clinicians employed at the dozens of hospital and healthcare systems in the U.S. that use Epic, including primary care providers (PCP), endocrinologist, and diabetes centers.
Specifically: As AEYE noted, these HCPs can now perform “on-the-spot” diabetic eye exams without physician interpretation and order an AI-based DR exam directly from a patient’s chart in Epic.
What will this process look like?
Essentially, just as AEYE Health instructs on its product website:
- To start: A nurse or medical assistant will capture one retinal image per eye via a portable camera integrated with the AEYE-DS.
- These results are then automatically (as in, within seconds) uploaded to a patient’s Epic medical record.
- Then, when (or if) the system detects signs of disease, an alert is automated and sent to ophthalmology for a “timely follow-up.”
How does reimbursement and billing work?
Per AEYE Health: “Full automation of reimbursement code billing and care gap reporting is also supported.”
Take note: AEYE-DS is categorized under the “first-ever AI-specific reimbursement code” in the U.S. (CPT code 9229).
Nice! Now, this Epic integration isn’t the first for AEYE Health, right?
Correct. In fact, the company has been busy over the last couple of years—see here for a look at its prior integrations across the U.S.