ZEISS updates CIRRUS 6000 OCT technology

ZEISS Medical Technology has released new features and enhancements to the CIRRUS 6000, a next-generation optical coherence tomography (OCT)/OCT-angiography (OCTA) system.

To be clear: This isn’t a new product, right?

Correct. Originally launched in 2019, the CIRRUS 6000 platform is designed to deliver:

• High-speed image capture at 100,000 scans per second
• High-definition (HD) imaging details
• Wider field of view (up to 12 mm in a single scan)
• Four imaging modes: posterior segment, anterior segment, OCTA, and fundus imaging
• Focus adjustment: -20D to +20D

Note: ZEISS noted that it also recently received FDA clearance.

And it’s definitely not the first OCT system ZEISS has developed?

Right. Previous systems (including previous CIRRUS generations) include:

• Advanced OCT solutions
  • CIRRUS HD-OCT 4000
    • Spectral-domain (SD)-OCT for posterior and anterior of the eye
  • CIRRUS 500/5000
    • Full-spectrum OCT/OCTA for retina and glaucoma diagnostics
• Research OCT solution
  • ZEISS PLEX Elite 9000 Swept-Source (SS) OCT

How is the 6000 different from the previous CIRRUS?

Compared to the most recent previous generation (the CIRRUS 5000), the 6000 features a camera capture rate that’s 100 kHz vs the 5000’s 27kHz—a major advantage for clinicians tracking patients with glaucoma.

Gotcha. So tell me more about the CIRRUS 6000’s features.

The platform provides “clinically-validated” applications for a few key therapeutic areas, each with unique capabilities:

• Retina
  • Macular change analysis
    • Stores patient historical data such as macular thickness change maps
• AngioPlex Metrix OCTA Quantification*
  • For macular and optic nerve head (ONH)*
    • Objectively assess and track progressive diseases (glaucoma and diabetic retinopathy [DR]) with quantification tools
    • Seven-layer segmentation (see here)*

*Disclaimer: AnglioPlex Metrix, ONH OCTA, and seven-layer segmentation are currently not available in the U.S.

• Glaucoma
  • CIRRUS retinal nerve fiber layer (RNFL) thickness deviation maps
  • Ganglion cell analysis (GCA) for macular glaucomatous damage identification
  • Combined ganglion cell layer (GCL)/inner plexiform layer (IPL) and RNFL thickness deviation maps
  • AutoCenter (patent algorithm) for automatically identifying the ONH via Bruch’s membrane opening in 3D
  • Guided Progression Analysis (GPA) provides trend and event-based analysis to detect change and quantify rate of change for key parameters
• Anterior segment
  • Anterior Segment Premier Module enables comprehensive imaging and anterior segment quantification

What else is new with this system?

It also features the “largest reference database across all OCT devices in the U.S. market,” according to ZEISS.

Exactly how big, you ask? It’s reported to house a comprehensive library of 870+ healthy eyes (triple the amount compared to prior versions), with more diversity and consideration for various optic disc sizes and age (18 to 88+).

Why this is important: The database may prove beneficial for customizing diagnostic approaches and ocular health / disease management plans for patients.

• And for patient data specifically: Raw data can now be transferred from previous ZEISS OCT systems (listed above).

How about its security?

But of course. The platform now includes new cybersecurity features to protect against potential cyber threats as well as provide advanced data security, instant disaster recovery, and enhanced password security, to name a few.

See here for additional cybersecurity features.

And its data storage/transfer capabilities?

Clinicians can share DICOM OP and OPT compressed data with ZEISS FORUM—an ophthalmic data management solution— and electronic medical records (EMRs) via the following imaging methods:

• JPEG2000 (J2K)
• JPEGBaseline

Nice! So where can I purchase this?

Click here (and scroll all the way down) to get in touch about adding this platform to your practice.

Editor's note: This article was updated on June 12, 2024, to clarify that AnglioPlex Metrix, ONH OCTA, and seven-layer segmentation are not currently available within the United States.